Chronic stress and joint pain could lead to Alzheimer’s by ‘inflaming your brain’

Chronic stress can lead to neuroinflammation which has far-reaching effects on the brain (Image: GETTY)

Neuroinflammation, a reaction in the brain or spinal cord, can lead to a host of health problems, many of which may be irreversible if not addressed promptly.

Chronic stress, along with unexpected conditions like joint pain or gut issues, can fuel neuroinflammation, which can significantly affect the brain's functions.

While this response is designed to protect and repair the brain when necessary, problems arise when the inflammation persists or becomes too intense.

Neuroinflammation is a common symptom of neurological and mood disorders, including Alzheimer’s Disease and Multiple Sclerosis, among others, but could also contribute to the development of these diseases, according to News Medical.

Stress initiates neuroinflammation to safeguard the brain, but chronic stress keeps this reaction active beyond its protective duties.

This can also occur due to other factors such as genetic mutations, infections, injuries to the central nervous system, autoimmune disorders, lifestyle factors, and even certain drugs.

Top causes of neuroinflammation include viral infections impacting the central nervous system, chronic conditions like rheumatoid arthritis, and gut inflammation. Certain autoimmune conditions and cancers, such as small cell lung cancer, also target neural tissue, triggering a protective response.

Lifestyle factors can significantly contribute to inflammation, with poor diet, metabolic syndrome, obesity, diabetes, sleep deprivation and stress all playing a part. Neuroinflammation can exacerbate mental health conditions like depression and anxiety, further impairing brain function and sparking a worsening cycle. 

The severity of neuroinflammation depends on its cause, duration, and progression, with severe cases potentially leading to cell death in the brain.

With limited treatment options available, it's crucial for individuals to manage controllable factors.

If not addressed, neuroinflammation can cause tissue damage and contribute to irreversible conditions like Multiple Sclerosis, Alzheimer’s Disease, and is believed to play a role in the development of Parkinson’s.